Mobio Interactive is a digital therapeutics company that focuses on developing innovative solutions to measure and improve mental health and well-being using cutting-edge technology. Here are the key aspects of what they offer and their approach:

Core Offerings:

1. Digital Therapeutics Platform - AmDTx:
   • AmDTx is Mobio Interactive's flagship product. It is a clinically validated digital therapeutic platform designed to enhance mental health and resilience. The platform utilizes AI-powered technologies to deliver personalized therapy programs.
2. AI and Machine Learning:
   • The platform employs computer vision and machine learning algorithms to measure mental well-being. Using facial photoplethysmography (PPG) and deep neural networks, it objectively quantifies stress, anxiety, and depression levels based on data collected via standard smartphone cameras.
3. Remote Patient Monitoring:
   • Mobio Interactive's technology enables remote patient monitoring by analyzing physiological biomarkers such as heart rate (HR) and heart rate variability (HRV) from video captures. This non-invasive method provides real-time insights into a patient’s mental state.

Compliance and Certifications:

• The platform is compliant with GDPR, HIPAA, and PHIPA standards. It also holds several certifications, including CE MDD Class I and ISO 27001, with ongoing efforts to obtain additional certifications such as CE MDR Class IIa and ISO 13485.

Scientific Validation:

• The company has conducted multiple randomized controlled trials to validate the effectiveness of their platform. Their technology has demonstrated significant reductions in anxiety, depression, and stress across various severity levels.
• Studies have shown their deep neural network can predict cognitive stress with 86% accuracy using only HR and HRV data from smartphone videos.

Published Trials and Studies

1. Prospective Real World Study on Therapy Prediction Algorithm Training
   • Description: This study involved 2,786 unique individuals participating in psychotherapy sessions via the AmDTx platform. It analyzed data from 67 "super users" who completed at least 28 sessions, examining the effectiveness of the therapy prediction algorithm.
   • Reference: ClinicalTrials.gov
2. AmDTx in Stress and Emotional Wellbeing
   • Description: This trial examined the impact of AmDTx on stress resilience and emotional well-being, showing that the platform significantly outperformed placebo controls.
   • Reference: ICHGCP
3. Effects of a Mindfulness App for Outpatients Waitlisted for Therapy
   • Description: This study evaluated the outcomes of using the AmDTx mindfulness app over three months, focusing on patients on waitlists for outpatient therapy.
   • Reference: ClinicalTrials.gov
4. Mindfulness-Based Intervention for Mild Traumatic Brain Injury
   • Description: This study used the AmDTx MBI-based app to provide a four-week mindfulness training program for children with mild traumatic brain injury, including guided meditations and journaling.
   • Reference: ClinicalTrials.gov
5. AmDTx-PCSP and Questionnaires in Lung Cancer
   • Description: This trial focused on using the AmDTx platform to support lung cancer patients, incorporating self-report questionnaires and mindfulness-based interventions.
   • Reference: ICHGCP